Source: Alex Lavoie
Leap Therapeutics and Quhuo Limited Lead Market Upswing with Significant Gains
Recent market activity has seen a number of companies posting substantial gains, amid a broader risk-on sentiment and company-specific catalysts. Among these top performers, Leap Therapeutics, Inc. (NASDAQ: LPTX) and Quhuo Limited (NASDAQ: QH) stand out with their exceptionally high growth rates.
Leap Therapeutics Posts a Massive 441.49% Surge
Leap Therapeutics, an oncology-focused biopharmaceutical company, saw its stock price jump by an impressive 441.49%, closing at $2.36. This substantial upswing was accompanied by a significantly larger trading volume than usual, with a total of 610,713,569 shares being traded.
Such a surge in biotech stocks often indicates significant developments such as regulatory milestones, trial readouts, or strategic collaborations that could potentially transform the investor landscape. This suggests that a substantial shift in expectations around Leap Therapeutics’ pipelines and partnerships could be on the horizon.
Quhuo Limited Grows by 68.01% Amid Heightened Trading Activity
Meanwhile, Quhuo Limited, the China-based workforce operations platform, saw its stock price rise by an impressive 68.01% to $1.39. This growth came on the heels of increased trading activity, with a total volume of 31,416,317 shares being traded.
This rally could signal a renewed confidence in the company’s growth prospects and operational execution. Quhuo recently announced a collaboration between its subsidiary, Lailai Information Technology, and the “Better Life No.1 Collective Fund Trust Plan” managed by China Foreign Economy and Trade Trust Co., Ltd. This strategic alliance aims to enhance the value of long-term rental properties by aligning industry and finance.
Quhuo’s wide 52-week range, from $0.735 to $169.11, highlights how changes in sentiment can significantly influence price volatility, particularly in smaller-cap stocks.
Other Significant Movers: CMCT and SPRU
In addition to Leap Therapeutics and Quhuo Limited, other companies also posted significant gains. Creative Media & Community Trust Corporation (NASDAQ:CMCT), a real estate investment trust focusing on Class A and creative office assets in major metropolitan markets, rose 61.48% to $8.09.
Investor enthusiasm for CMCT likely stems from strategic portfolio repositioning and effective capital allocation decisions. Recently, CMCT entered into an agreement to sell its lending division to PG FR Holding, LLC, an affiliate of the Atlanta-based Peachtree Group. This move signifies a shift towards focusing more on core real estate operations, potentially offering more balance-sheet flexibility.
Additionally, Spruce Power Holding Corporation (NASDAQ:SPRU), a provider of residential solar and related clean-energy services, saw its shares rise 45.98% to $4.45. The company recently reported a third-quarter 2025 revenue of $30.7 million, up 44% year over year, and a total cash balance of $98.8 million as of September 30, 2025—an $8.3 million increase from the prior quarter. These metrics underscore improving scale and liquidity, trends that investors often favour in the distributed energy space.
Looking Ahead
These sharp advances across sectors such as biotechnology, real estate, and clean energy illustrate how improving fundamentals, capital strategy decisions, and sector-specific catalysts can drive rapid stock repricing. Market participants will be keeping an eye out for follow-up developments—such as additional clinical data, deal closings, or sustained cash-flow trends—to assess whether these gains are likely to endure.